| NeTech has successfully constructed vinyl polymers
of oligosaccharides containing galactose, glucose and others. Such
polyvinyl polymers of oligosaccharides may well be attached to resin
surfaces in spite of difficulty of binding sugar compounds themselves
onto resin surface. R-Gal, reconstructed galactose, is easily coated
onto slide glasses which will be utilized as a selective separator
of blood cells. It is important to separate specific type of blood
cell from venous or cord blood samples or from bone marrows which
may contain mature cells like erythrocytes, leukocytes, and platelets,
and immature hematopoietic cells. For example, separation and purification
of stem cells from cord blood is important for organ transplantation
with low risk of rejection. Separation of fetal cells released into
mother blood circulation will enable non-invasive prenatal diagnosis
and detection of leukemia cells in peripheral blood will offer sensitive
diagnosis of leukemia. Thanks to recent progress of genetic analyses,
non-invasive isolation of fetal cells from mother blood samples will
lead to high quality tests and therapy of genetic diseases in early
stages. |
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